Figure 2.

Increased numbers of ESAT-6-specific IFN-γ-producing cells in the pericardial fluid of HIV-1-uninfected patients. PBMCs and PFCs were assessed for antigen-specific IFN-γ responses by ELISpot assay. Each circle represents the number of IFN-γ spot forming cells/10⁶ cells in response to ESAT-6 and CFP-10, corrected for unstimulated control wells. The number of ESAT-6 specific IFN-γ spot forming cells/10⁶ cells was significantly higher in the pericardial fluid of the HIV-1-uninfected patients compared with HIV-1-infected patients (p=0.009, Mann–Whitney U test).