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. 2012 Jan 6;26(3):379–388. doi: 10.1038/eye.2011.218

Table 5. Published quality of life studies assessing EuroQOL-5D (EQ-5D) in ophthalmic diseases.

Study Disease Population EQ-5D Visual acuity severity profile Pearson's/Spearman's correlation coefficient for visual acuity
This study (n=338) AMD Singapore 0.89 Mean BEVA: 0.20 Mean WEVA: 0.65 Mean Weighted VA: 0.31 BEVA: −0.291 WEVA: −0.247 Weighted VA: −0.305
Soubrane et al6 (n=401) AMD France, Germany, Spain, UK, Canada 0.65 Mean BEVA: 0.6 Not assessed, but no association found with BEVA
Cruess et al33 (n=67) AMD Canada 0.64 BEVA >20/40: 14.9% >20/80–20/40: 10.4% >20/200–20/80: 31.3% >20/400–20/200: 25.4% 20/400 or worse: 13.4% Not assessed, but no association found with BEVA
Lotery et al34 (n=75) Neovascular AMD UK 0.67 Better than 20/40 to worse than 20/400; no percentages given Not assessed, but no association found with BEVA
Espallargues et al5 (n=209) AMD UK 0.72 Mean BEVA: 1.01 Mean WEVA: 1.68 BEVA: −0.09
Clark et al35 (n=19) Post-operative endophthalmitis Australia 0.66 No visual impairment (VI): 47% Unilateral VI: 47% Bilateral VI: 6% Not assessed
Aspinall et al36 (n=72) Glaucoma UK 0.76 78% with VA better than 6/12 in both eyes Not assessed, but significant association found with VA (P<0.01)
Kobelt et al37 (n=199) Glaucoma Sweden 0.80 Mean BEVA: 0.63 Mean WEVA: 0.87 Weighted VA: 0.80 Not assessed, but no association found
Lloyd et al38 (n=101) Diabetic retinopathy UK Not assessed 6/6–6/9: 67% 6/12–6/18: 13% 6/24–6/36: 10% 6/60–6/120: 7% CF–HM: 3% Not assessed; R2=0.123
Polack et al39 (n=217) Cataract Bangladesh Not assessed BEVA <6/24–6/60: 26% <6/60–3/60: 19% <3/60–>PL: 14% PL: 41% Not assessed
Polack et al40 (n=196) Cataract Kenya Not assessed BEVA <6/24–6/60: 39.8% <6/60–3/60: 20.9% <3/60–>PL: 18.4% PL: 20.9% Not assessed
Datta et al41 (n=306) Cataract UK 0.73 Mean BEVA: 0.28 Standardised β: 0.01
Lengalaan et al42 (n=128) Visually impaired Netherlands 0.73 Not reported Not assessed
Rajagopalan et al43 (n=32) Sjögren's syndrome keratoconjunctivitis sicca USA, Canada 0.74 Not reported Not assessed