Table 3. Summary of linear regression analysis for refill adherence.

Variable	Coefficient	P-value	95% CI
Intervention	9.8	0.017	1.82–17.83
IOP fluctuation 0–24 months	−3.3	0.017	−6.02 to −0.62
Changes in clinical management between 13 and 24 months	−10.6	0.014	−19.01 to −2.21

R²=0.46, adjusted R²=0.21, ANOVA F=10.39, df=3,117, P<0.001.