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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Exp Eye Res. 2010 Dec 10;93(3):321–327. doi: 10.1016/j.exer.2010.12.003

Fig. 3.

Fig. 3

Effects of inhibitors of phosphodiesterase and nitric oxide synthase on responses to L-arg and SNP in carbachol (CARB)-precontracted monkey ciliary muscle (CM) strips. L-arg and SNP responses without inhibitor are taken from the concentration–response curves in Fig. 2 for reference. Inhibitor data are expressed as the %Δ in the initial CARB contraction force (in the presence of the inhibitor) for each vector (longitudinal = LONG, black bars; circular = CIRC, white bars) versus the concentration of each compound (*p < 0.05, paired t-test). N is the number of different monkey CMs represented. A given CM may have received more than one concentration of a given agent. Maximal relaxation of CM contraction response in the presence of CARB + test agent is shown. See data in Table 3. Continued incubation of the CM with the given agent in the presence of CARB resulted in partial attenuation of the relaxation response or enhancement of contractility response (not shown).