Table 3.

Association between periodontitis and head and neck cancer stratified by tumor site (N = 473).

Alveolar bone loss (per millimeter)	N (cases/controls)	Crude OR [95% CI]*	Adjusted†  OR [95% CI]
All HNSCC patients	266/207	3.85 [2.96–5.01]	4.36 [3.16–6.01]
Oral cavity SCC patients	100/207	3.26 [2.44–4.36]	4.52 [3.03–6.75]
Oropharyngeal SCC patients	115/207	3.06 [2.29–4.07]	3.64 [2.54–5.22]
Laryngeal SCC patients	51/207	3.75 [2.60–5.41]	2.72 [1.78–4.16]

*Odds ratios and their 95% confidence intervals.

^†Adjusted odds ratios were derived from multiple logistic regression analysis including age at diagnosis, gender, race/ethnicity, marital status, smoking status, alcohol use, ABL, and missing teeth.