Table I.

Aceclofenac loading and encapsulation efficiency in zein microspheres

Formulation code	Drug/polymer (mg)	Concentration of cross-linker (ml)	Drug loading (% w/w)a	Encapsulation efficiency (% w/w)b
F 1	100:500	0	4.92 ± 0.05	24.5 ± 0.38
F 2	100:300		5.05 ± 0.07	15.15 ± 0.30
F 3	250:500		8.63 ± 0.05	14.38 ± 0.23
F 4	100:500	0.25	4.74 ± 0.21	21.34 ± 0.94
F 5	100:300		4.77 ± 0.40	12.87 ± 1.08
F 6	250:500		8.70 ± 0.54	26.11 ± 1.62
F 7	100:500	0.5	5.25 ± 0.34	23.58 ± 1.53
F 8	100:300		4.28 ± 0.37	11.56 ± 1.01
F 9	250:500		6.67 ± 0.55	20.02 ± 1.66
F 10	100:500	1	4.79 ± 0.45	21.54 ± 2.06
F 11	100:300		4.38 ± 0.66	11.82 ± 1.77
F 12	250:500		6.85 ± 0.56	20.53 ± 1.68

^aDrug loading (percent weight/weight) = amount of drug in microspheres/amount of microspheres taken

^bEncapsulation efficiency (percent weight/weight) = amount of drug in microspheres/drug initially added