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Composition of ATRA-Loaded NLC Formulations
| Composition | Formulations | |||
|---|---|---|---|---|
| S/CP | M/CP | S/O/CP | M/O/CP | |
| ATRA (mg/g of NLCs) | 1,3,5,7,9 | 1,3,5,7,9 | 1,3,5,7,9 | 1,3,5,7,9 |
| Oil phase (%) | ||||
| Soybean oil (S) | 15 | – | 11.25 | – |
| Medium chain triglyceride (M) | – | 15 | – | 11.25 |
| Oleic acid (O) | – | – | 3.75 | 3.75 |
| Cetyl palmitate (CP) | 15 | 15 | 15 | 15 |
| Lecithin (%) | 1.2 | 1.2 | 1.2 | 1.2 |
| BHT (%) | 0.002 | 0.002 | 0.002 | 0.002 |
| Polysorbate-80 (%) | 8 | 8 | 8 | 8 |
| Distilled water qs. | 100 | 100 | 100 | 100 |
