Table V.
Cumulative ATRA Released of ATRA-Loaded NLCs at 37 ± 0.5°C
| Formulations | % Cumulative drug released at | |||
|---|---|---|---|---|
| 2 h | 8 h | 24 h | 48 h | |
| ATRA (control) | 0.0009 ± 0.0001 | 0.0034 ± 0.0004 | 0.0149 ± 0.001 | 0.0281 ± 0.003 |
| S/CP-ATRA 1 mg/g | 0.32 ± 0.03 | 0.93 ± 0.08 | 2.57 ± 0.15 | 4.16 ± 0.29 |
| S/CP-ATRA 3 mg/g | 0.26 ± 0.04 | 0.95 ± 0.11 | 2.54 ± 0.10 | 4.31 ± 0.16 |
| M/CP-ATRA 1 mg/g | 0.25 ± 0.01 | 1.01 ± 0.06 | 2.44 ± 0.17 | 4.06 ± 0.22 |
| M/CP-ATRA 3 mg/g | 0.30 ± 0.05 | 1.09 ± 0.10 | 2.65 ± 0.10 | 4.34 ± 0.15 |
| M/CP-ATRA 5 mg/g | 0.26 ± 0.02 | 0.95 ± 0.14 | 2.64 ± 0.15 | 4.09 ± 0.19 |
| S/O/CP-ATRA 1 mg/g | 0.25 ± 0.01 | 1.00 ± 0.00 | 2.54 ± 0.13 | 4.15 ± 0.14 |
| S/O/CP-ATRA 3 mg/g | 0.26 ± 0.01 | 0.99 ± 0.07 | 2.54 ± 0.21 | 4.25 ± 0.13 |
| S/O/CP-ATRA 5 mg/g | 0.27 ± 0.01 | 1.06 ± 0.13 | 2.42 ± 0.12 | 4.10 ± 0.11 |
| S/O/CP-ATRA 7 mg/g | 0.24 ± 0.02 | 0.98 ± 0.17 | 2.54 ± 0.15 | 4.08 ± 0.17 |
| S/O/CP-ATRA 9 mg/g | 0.27 ± 0.02 | 1.05 ± 0.08 | 2.58 ± 0.16 | 4.12 ± 0.17 |
| M/O/CP-ATRA 1 mg/g | 0.26 ± 0.01 | 0.95 ± 0.10 | 2.38 ± 0.16 | 4.09 ± 0.18 |
| M/O/CP-ATRA 3 mg/g | 0.27 ± 0.02 | 1.00 ± 0.02 | 2.57 ± 0.19 | 4.24 ± 0.08 |
| M/O/CP-ATRA 5 mg/g | 0.24 ± 0.02 | 0.93 ± 0.08 | 2.51 ± 0.02 | 4.15 ± 0.13 |
| M/O/CP-ATRA 7 mg/g | 0.25 ± 0.01 | 1.01 ± 0.13 | 2.59 ± 0.11 | 4.15 ± 0.14 |
| M/O/CP-ATRA 9 mg/g | 0.25 ± 0.02 | 1.04 ± 0.08 | 2.53 ± 0.08 | 4.14 ± 0.12 |