Table II.

Preparation of Drug–Ovalbumin Complex

Drug–ovalbumin complex	Phase diagram composition (%)			Observation	Particle size D[4,3] μm
	Drug (%)	Ovalbumin (%)	Water (%)
PEO13	5.1	15.4	79.5	Agglomeration	45.82 ± 3.31
PEO12	7.4	14.8	77.8	Agglomeration	43.29 ± 2.80
PEO23	9.5	14.3	76.2	Microparticles	17.28 ± 0.32*
PEO11	13.3	13.3	73.3	Microparticles	15.33 ± 1.19*
PEO32	18.2	12.1	69.7	Agglomeration	41.03 ± 2.63
VPO13	2.9	8.8	88.2	Agglomeration	47.58 ± 3.15
VPO12	3.6	7.1	89.3	Agglomeration	46.10 ± 3.79
VPO23	4.0	6.0	90.0	Microparticles	18.53 ± 1.15*
VPO11	4.5	4.5	90.9	Microparticles	16.61 ± 1.11*
VPO32	5.0	3.3	91.7	Agglomeration	42.00 ± 2.18
PPO13	2.6	7.7	89.7	Agglomeration	49.69 ± 2.47
PPO12	3.0	6.1	90.9	Agglomeration	48.51 ± 2.80
PPO23	3.3	5.0	91.7	Microparticles	20.08 ± 1.70*
PPO11	3.7	3.7	92.6	Microparticles	17.25 ± 1.05*
PPO32	4.0	2.7	93.3	Agglomeration	43.08 ± 2.94
PCO13	1.1	3.4	95.5	Agglomeration	51.04 ± 2.53
PCO12	1.2	2.4	96.4	Agglomeration	49.86 ± 2.18
PCO23	1.3	1.9	96.9	Microparticles	25.05 ± 1.30*
PCO11	1.3	1.3	97.4	Microparticles	28.06 ± 1.18*
PCO32	1.3	0.9	97.8	Agglomeration	45.21 ± 3.23
CUO13	0.5	1.4	98.2	Microparticles	71.81 ± 2.89*
CUO12	0.6	1.2	98.2	Agglomeration	68.13 ± 3.85*
CUO23	0.7	1.1	98.1	Agglomeration	90.62 ± 3.40
CUO11	0.9	0.9	98.1	Agglomeration	96.03 ± 2.37
CUO32	1.1	0.8	98.1	Agglomeration	98.73 ± 2.32

*p < 0.05