FIGURE 2.

Secondary catechin treatment fully prevents age-dependent splenocyte adhesion onto the endothelium. Splenocyte adhesion onto the native endothelium of aortic segments isolated from 3-month old mice, 12-month old untreated mice and 12-month old mice treated for the last 3 months (+ CAT 3) or the last 9 months (+ CAT 9) with catechin. Responses were obtained either in basal conditions (baseline) or following stimulation of the native endothelium with histamine (0.1 μM).

Data are mean±SEM (A) and the corresponding individual data (B) of n = 5–29.

*: P<0.05 compared to 3-month old mice; †: P<0.05 compared to 12-month old mice; ‡: P<0.05 compared to baseline.