Table 7.
Interaction of the Ru compounds with CT DNA after 96 h of incubation at 37 °C
Compound | nmol Ru/mg DNA base | Ru/basea | base/Ru |
---|---|---|---|
[Ru2(p-cymene)2(L1)2]Cl2 | 42.7 | 0.014 | 71 |
[Ru2(p-cymene)2(L2)2](PF6)2 | 28.2 | 0.009 | 108 |
[Ru2(p-cymene)2(L3)2](PF6)2 | 22.7 | 0.008 | 134 |
[Ru2(p-cymene)2(L4)2]Cl2 | 37.5 | 0.013 | 80 |
ruthenium (mol) per DNA base (mol).