Table 1.

Events and time table

					Intervention period			Follow-up period
Procedure	Source	Person	No. of items	Duration (min.)	T0	T3	T6	T12
Written informed consent	letter	patient			X
Demographics1	patient file	research assistant			X
Depression
Depression history2	patient file	research assistant	2		X
HRSD3	interview	blind rater	17	20	X	X	X	X
IDS-SR4	questionnaire	patient	30	10	X	X	X	X
Bearableness (VAS)	questionnaire	patient	1		X	X	X	X
Metabolic syndrome
Length	physical test	research assistant		1	X
Weight	physical test	research assistant		1	X	X	X	X
Waist circumference	physical test	research assistant		1	X	X	X	X
Blood pressure	physical test	research assistant		1	X	X	X	X
Smoking/alchohol intake	questionnaire	patient		1	X	X	X	X
Laboratory assesment6	physical test	laboratory		2	X	X	X	X
Quality of Life
WHO-DAS7	questionnaire	patient	36		X	X	X	X
Pain
GCPS8	questionnaire	patient	7		X	X	X	X
Bearableness (VAS)	questionnaire	patient	1		X	X	X	X
Anxiety
BAI9	questionnaire	patient	21		X	X	X	X
Cost effectiveness
TIC-P10	quest./pnt file	pnt/research assistant		26	X		X	X
Euroqol	questionnaire	patient		5	X		X	X
Subjective health (VAS)	questionnaire	patient		1	X		X	X
Fitness
Submaximal cycle test	physical test	research assistant		10	X	X	X	X
Grip strength	physical test	research assistant		2	X	X	X	X
Exercise intensity (HR)11	physical test	exercise instructor			during training sessions
Personality
NEO PI-R12	questionnaire	patient	60		X
Physical activity
SQUASH13	questionnaire	patient	12		X	X	X	X
Additional Measures
LEQ14	questionnaire	patient	12		X	X	X	X
Compliance	registration	exercise instructor			during training sessions
POMS15	questionnaire	patient	32		during training sessions
Evaluation Intervention16	questionnaire	patient					X

1: Date of birth, sex, education, ethnicity, income, professional status, living situation, marital status

2: Number and duration of former episodes, duration current episode

3: Hamilton Rating Scale of Depression (or HAMD)

4: Inventory of Depressive Symptomatology - Self Report

6: fasting glucose, triglycerides, total cholesterol, HDL- cholesterol, cholesterol/HDL-ratio, creatinine, MDRD

7: World Health Organisation- Disability Assessment Schedule

8: Graded Chronic Pain Scale

9: Beck Anxiety Inventory

10: Trimbos/iMTA questionnaire for Costs associated with Psychiatric Illness

11: Polar RS 800 CX Run

12: Revised NEO Personality Inventory

13: Short QUestionnaire to ASses Health enhancing physical activity

14: Life Events Questionnaire

15: Profile of Mood State

16: Only for patients who participated in the intervention