Table 2.

¹⁸F-activity uptake 40 min after injection of [¹⁸F]CFT into the brains of control and pretreated rats

Brain region	Control n = 6	GBR12909 n = 7	Nisoxetine n = 6	Fluoxetine n = 6
Striatum	1.55 ± 0.78	0.49 ± 0.18*	1.48 ± 0.22	1.38 ± 0.75
Locus coeruleus	0.67 ± 0.29	0.37 ± 0.11**	0.23 ± 0.05*	0.47 ± 0.16
Frontal cortex	0.32 ± 0.08	0.23 ± 0.04	0.26 ± 0.03	0.33 ± 0.13
Cerebellum	0.20 ± 0.04	0.15 ± 0.04	0.17 ± 0.02	0.23 ± 0.09

*p < 0.01 compared with control;**p < 0.05 compared with control. Uptake values are in percent injected dose per gram tissue. All values are means ± SD. The effect of pretreatment was compared with the uptake values of control rats. Means were considered significantly different when p < 0.05.