Table 2.
Univariate analysis of risk factors for AKI
| FACTOR | AKI | No AKI | Odds ratio (95%CI) |
P value |
|---|---|---|---|---|
| NGAL > 89 ng/ml | 15/22 (68%) | 20/68 (29%) | 5.1 (1.8-14.5) | 0.003* |
| NGAL > 149 ng/ml | 10/22 (45%) | 8/68 (12%) | 6.1 (2.0-18.8) | 0.002* |
| Age ≥ 80 years | 10/22 (45%) | 33/68 (49%) | 1.3 (0.4-3.3) | 0.81 |
| eGFR < 60 ml/min/1.73 m2 | 19/22 (86%) | 35/68 (51%) | 6.0 (1.6-22.0) | 0.005* |
| Diabetes | 10/22 (45%) | 32/68 (47%) | 0.9 (0.4-2.5) | 0.90 |
| Hypertension | 16/22 (72%) | 45/68 (66%) | 1.4 (0.5-3.9) | 0.57 |
| Loop diuretic ↑1 | 15/22 (68%) | 43/68 (63%) | 1.2 (0.4-3.5) | 0.64 |
| Nephrotoxic drug2 | 7/22 (32%) | 25/68 (37%) | 0.8 (0.3-2.2) | 0.64 |
| IV Contrast | 6/22 (27%) | 15/68 (22%) | 1.3 (0.4-4.0) | 0.64 |
| Sepsis | 1/22 (4%) | 1/68 (1.5%) | 3.2 (0.2-54.0) | 0.43 |
| Shock | 2/22 (9%) | 4/68 (6%) | 1.6 (0.3-9.4) | 0.63 |
| Myocardial Infarction | 6/22 (27%) | 9/68 (13%) | 2.5 (0.8-8.0) | 0.19 |
| Urinary Infection | 3/22 (14%) | 5/68 (7%) | 2.0 (0.4-9.1) | 0.40 |
*p < 0.05
1 Introduction of loop diuretic or increase in usual dose of ≥ 50% over baseline for at least 24 hours (including bolus doses)
2 At least one dose of agent with potential renal toxicity including ACE inhibitor, angiotensin receptor blocker, non-steroidal anti-inflammatory drug, spironolactone, aminoglycoside antibiotic etc.