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. 2012 Mar 12;7(3):e32223. doi: 10.1371/journal.pone.0032223

Table 1. Demographical and Clinical Characteristics of the Study Subjects.

Characteristics IGR Cases Controls P Value
Number of Subjects 262 603
Age, years 50.11 (11.8) 49.83 (10.02) 0.737
Male, n (%) 141 (53.82) 361 (59.87) 0.100
BMI, kg/m2 25.00 (23.31–26.73) 23.23 (21.30–24.98) <0.001
Smoking, n (%) 61 (23.28) 207 (34.33) 0.001
Alcohol, n (%) 58 (22.14) 194 (32.17) 0.003
Family History of Diabetes, n (%) 39 (14.89) 35 (5.80) <0.001
Hypertention, n (%) 85 (32.44) 135 (22.39) 0.002
FPG (mmol/L) 5.97 (0.64) 4.81 (0.66) <0.001
FPI (µU/ml) 9.60 (6.68–13.16) 6.52 (4.76–8.52) <0.001
OGTT2h (mmol/L) 9.22 (8.45–10.12) 7.47 (7.09–7.76) <0.001
HbA1c (%) 5.89 (0.57) 5.50 (0.33) <0.001
HOMA-beta 80.69 (50.55–119.67) 100.25 (71.71–137.38) <0.001
HOMA-IR 2.52 (1.70–3.67) 1.40 (0.94–1.87) <0.001
TC (mmol/L) 4.40 (3.67–5.16) 4.36 (3.87–4.95) 0.522
TG (mmol/L) 1.41 (1.00–1.97) 1.08 (0.67–1.53) <0.001
HDL-C (mmol/L) 1.22 (1.07–1.44) 1.28 (1.13–1.46) 0.040
CRP (ng/ml) 12.01 (4.47–22.75) 8.55 (3.97–14.61) <0.001

Abbreviations: IGR, impaired glucose regulation; BMI, body mass index; FPG, fasting plasma glucose; FPI, fasting plasma insulin; OGTT2h, 2-h post-glucose load; HOMA-beta, homeostasis model assessment of beta cell function; HOMA-IR, homeostasis model assessment of insulin resistance; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; CRP, C-reactive protein.

Data are presented as number (percentage) for categorical data, mean (standard deviation) for parametrically distributed data or median (interquartile range) for nonparametrically distributed data.