Table 1. Demographical and Clinical Characteristics of the Study Subjects.
Characteristics | IGR Cases | Controls | P Value |
Number of Subjects | 262 | 603 | |
Age, years | 50.11 (11.8) | 49.83 (10.02) | 0.737 |
Male, n (%) | 141 (53.82) | 361 (59.87) | 0.100 |
BMI, kg/m2 | 25.00 (23.31–26.73) | 23.23 (21.30–24.98) | <0.001 |
Smoking, n (%) | 61 (23.28) | 207 (34.33) | 0.001 |
Alcohol, n (%) | 58 (22.14) | 194 (32.17) | 0.003 |
Family History of Diabetes, n (%) | 39 (14.89) | 35 (5.80) | <0.001 |
Hypertention, n (%) | 85 (32.44) | 135 (22.39) | 0.002 |
FPG (mmol/L) | 5.97 (0.64) | 4.81 (0.66) | <0.001 |
FPI (µU/ml) | 9.60 (6.68–13.16) | 6.52 (4.76–8.52) | <0.001 |
OGTT2h (mmol/L) | 9.22 (8.45–10.12) | 7.47 (7.09–7.76) | <0.001 |
HbA1c (%) | 5.89 (0.57) | 5.50 (0.33) | <0.001 |
HOMA-beta | 80.69 (50.55–119.67) | 100.25 (71.71–137.38) | <0.001 |
HOMA-IR | 2.52 (1.70–3.67) | 1.40 (0.94–1.87) | <0.001 |
TC (mmol/L) | 4.40 (3.67–5.16) | 4.36 (3.87–4.95) | 0.522 |
TG (mmol/L) | 1.41 (1.00–1.97) | 1.08 (0.67–1.53) | <0.001 |
HDL-C (mmol/L) | 1.22 (1.07–1.44) | 1.28 (1.13–1.46) | 0.040 |
CRP (ng/ml) | 12.01 (4.47–22.75) | 8.55 (3.97–14.61) | <0.001 |
Abbreviations: IGR, impaired glucose regulation; BMI, body mass index; FPG, fasting plasma glucose; FPI, fasting plasma insulin; OGTT2h, 2-h post-glucose load; HOMA-beta, homeostasis model assessment of beta cell function; HOMA-IR, homeostasis model assessment of insulin resistance; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; CRP, C-reactive protein.
Data are presented as number (percentage) for categorical data, mean (standard deviation) for parametrically distributed data or median (interquartile range) for nonparametrically distributed data.