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. 2012 Mar 12;7(3):e32659. doi: 10.1371/journal.pone.0032659

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Trenor et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Simulated APs (panel A), [Ca²⁺]_i transients (panel B), and Na⁺/Ca²⁺ exchanger (NCX) activity (panel C) at 1-Hz pacing rate in control (dark line) and in heart failure (HF) conditions (light line). The insets show experimental recordings of Priebe and Beuckelmann et al. [5] (panel A) and Weber et al. [31] (panel B).