Table 1. Kif3a deletion in osteoblasts and osteocytes has no effect on tibial midshaft geometry.
| Control (n = 25) | Col2.3-Cre;Kif3a fl/fl (n = 22) | p-value | |
| Ulna | |||
| Bone Length (mm) | 14.4 ± 0.2 | 13.99 ± 0.2 | N.S. |
| Imin (mm4) | 0.0046 ± 0.0002 | 0.0048 ± 0.0002 | N.S. |
| Imax (mm4) | 0.0160 ± 0.0009 | 0.0147 ± 0.0006 | N.S. |
| Tibia Midshaft | |||
| Cortical Thickness (mm) | 0.238 ± 0.003 | 0.239 ± 0.008 | N.S. |
| Imin (mm4) | 0.077 ± 0.005 | 0.066 ± 0.006 | N.S. |
| Imax (mm4) | 0.128 ± 0.006 | 0.109 ± 0.010 | N.S. |
| pMOI (mm4) | 0.205 ± 0.011 | 0.175 ± 0.016 | N.S. |
Imin and Imax are maximum and minimum second moment of inertia, respectively. pMOI is polar moment of inertia. Cortical bone geometry in 16 week old skeletally mature Colα1(I) 2.3-Cre;Kif3afl/fl and control mice was assessed using as microCT. Data presented as mean±SEM. N.S. is not significant (p>0.15).