Table 4. Clinical TNM staging and RECK genotypic frequencies in 135 HCC patients.
Variable | rs10814325 | rs16932912 | rs11788747 | rs10972727 | ||||||||
TT (N = 21) | TC+CC (N = 144) | p value | GG (N = 64) | GA+AA (N = 71) | p value | AA (N = 83) | AG+GG (N = 52) | p value | TT (N = 76) | TA+AA (N = 59) | p value | |
n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |||||
Clinical stage | ||||||||||||
Stage I/II | 12 (57.1%) | 72 (63.2%) | 0.601 | 38 (59.4%) | 46 (64.8%) | 0.517 | 54 (65.1%) | 30 (57.7%) | 0.390 | 49 (64.5%) | 35 (59.3%) | 0.540 |
Stage III/IV | 9 (49.2%) | 42 (36.8%) | 26 (40.6%) | 25 (35.2%) | 29 (34.9%) | 22 (42.3%) | 27 (35.5%) | 24 (40.7%) | ||||
Tumor size | ||||||||||||
≦T2 | 13 (61.9%) | 72 (64.9%) | 0.791 | 41 (64.1%) | 46 (64.8%) | 0.930 | 55 (66.3%) | 32 (61.5%) | 0.577 | 51 (67.1%) | 36 (61.0%) | 0.464 |
>T2 | 8 (38.1%) | 42 (35.1%) | 23 (35.9%) | 25 (35.2%) | 28 (33.7%) | 20 (38.5%) | 25 (32.9%) | 23 (39.0%) | ||||
Lymph node metastasis | ||||||||||||
No | 19 (90.5%) | 109 (95.6%) | 0.298 | 60 (93.8%) | 68 (95.8%) | 0.442 | 79 (95.2%) | 49 (94.2%) | 0.550 | 72 (94.7%) | 56 (94.9%) | 0.639 |
Yes | 2 (9.5%) | 5 (4.4%) | 4 (6.3%) | 3 (4.2%) | 4 (4.8%) | 3 (5.8%) | 4 (5.3%) | 3 (5.1%) | ||||
Distant metastasis | ||||||||||||
No | 19 (90.5%) | 110 (96.5%) | 0.235 | 59 (92.2%) | 70 (98.6%) | 0.082 | 83 (100.0%) | 46 (88.5%) | 0.003* | 75 (98.7%) | 54 (91.5%) | 0.057 |
Yes | 2 (9.5%) | 4 (3.5%) | 5 (7.8%) | 1 (1.4%) | 0 (0%) | 6 (11.5%) | 1 (1.3%) | 5 (8.5%) |
p value<0.05.