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. 2012 Mar 12;7(3):e33546. doi: 10.1371/journal.pone.0033546

Figure 5. Effect of DSS treatment and L-Arg supplementation on L-Arg metabolic pathways.

Figure 5

Mice received 4% DSS ± 1% L-Arg in the drinking water as in Figures 34. (A) At sacrifice on day 10, a piece of colon was obtained for RNA isolation or polyamine determination by HPLC. (A–G) Tissue mRNA levels of the genes indicated, as assessed by real-time PCR. (H) Tissue polyamine levels were assessed by HPLC as described in the Methods. n = 4–15 per group. *p<0.05, **p<0.01, ***p<0.001 vs. control. §p<0.05 vs. DSS.