Table 1.
The kinetic data and Co2+ selectivity of clones 11 and 18 and the 11B trans-cleaving DNAzymes. Kinetic data was obtained at pH 7.0 with metal ions (500 µm) and NaCl (500 mm).
Construct | kobs [min−1] | Co:Zn | Co:Pb | ||
---|---|---|---|---|---|
Co2+ | Zn2+ | Pb2+ | |||
Clone 11 | 0.18 | 0.11 | 0.040 | 1.6 | 4.5 |
Clone 18 | 0.044 | 0.096 | 0.078 | 0.46 | 0.56 |
11B | 0.088 | 0.15 | 0.079 | 0.59 | 1.1 |