Table 5.

Effect of metastable structures on selectivity. The predicted metastable structures for selected constructs are compared with the observed metal selectivity. Constructs predicted to form only the 11B structure show higher Co²⁺ selectivity. All metal selectivity values were determined at 50 µm metal concentration unless otherwise stated.

Construct	Predicted structure	Co:Zn	Co:Pb
Clone 11	11A/11B	1.6[a]	4.5[a]
Clone 18	11A	0.46[a]	0.56[a]
11B/Sub	11B/11B’	0.59±0.06[a]	1.1±0.2[a]
		0.88±0.091	1.1±0.1
11B5/Sub3	11A/11B	0.41[a]	0.69[a]
11B5/Sub	11B/11B’	0.05[a]	1.1[a]
11B3/Sub2	11B/11B’	0.06[a]	0.12[a]
11BNick1	11B/11B’	0.56±0.15	0.55±0.16
11BNick2	11B	1.4±0.3[a]	2.4±0.5[a]
		1.6±0.2	3.2±0.7
11BNick3	11B/11B’	0.71±0.22	1.7±0.3
11BNick4	11B/11B’	0.79±0.14	1.5±0.3
11BNick5	11B	0.67±0.11	1.1±0.3
11BNick6	11B	0.64±0.03	1.1±0.3
11BNick7	11B	0.76±0.20[a]	1.5±0.4[a]
		0.92±0.09	2.8±0.7
11BNick8	11B	0.67±0.08[a]	1.4±0.2[a]
		0.76±0.07	2.2±0.8
11B14	11A/11B/11B’	0.55±0.06[a]	0.70±0.18[a]
		0.85±0.15	1.8±0.27
11B15	11A/11B/11B’	0.56±0.10[a]	0.76±0.17[a]
		0.87±0.15	1.8±0.4

^[a]Values obtained at 500 µm.