TABLE 2. Cohort Demographics: All ABO Compatible Pairs, Matched ABO Compatible Controls, and ABO Incompatible Pairs.
| ABOc (all) | ABOc (matched) | ABOi | |
|---|---|---|---|
| N | 77,455 | 3,679 | 738 |
| Recipient Characteristics | |||
| Age | 45.4 [13.7] | 46.8 [13.2] | 46.9 [13.6] |
| Female (%) | 40.8 | 41.6 | 42.1 |
| BMI | 26.7 [5.5] | 27.0 [5.6] | 26.9 [5.9] |
| College Educated (%) | 53.8 | 55.4 | 59.4 |
| Ethnicity (%) | |||
| Caucasian | 68.1 | 66.9 | 67.2 |
| African American | 14.6 | 15.6 | 18.2 |
| Hispanic | 12.3 | 12.7 | 10.3 |
| Private Insurance (%) | 58.1 | 59.4 | 59.4 |
| Diabetes (%) | 27.7 | 27.3 | 27.5 |
| Sensitizing Events (%) | |||
| Previous Transplant | 11.7 | 15.7 | 16.9 |
| Previous Transfusion | 19.7 | 12.6 | 10.9 |
| Previous Pregnancy | 25.6 | 27.5 | 26.3 |
| Peak %PRA | 10.2 [22.4] | 15.2 [28.3] | 15.9 [29.5] |
| Years of RRT | 2.3 [4.2] | 2.9 [5.1] | 3.0 [5.0] |
| Primary Diagnosis (%) | |||
| Diabetes | 23.1 | 22.6 | 22.6 |
| Hypertension/Large Vessel Disease | 18.2 | 17.8 | 15.9 |
| Polycystic Kidney Disease | 9.9 | 11.4 | 10.3 |
| Glomerulonephritis | 26.1 | 25.0 | 25.6 |
| Donor/Transplant Characteristics | |||
| Donor Age | 40.3 [11.1] | 40.3 [11.2] | 42.5 [11.4] |
| Female Donor (%) | 58.9 | 59.2 | 60.7 |
| Mean HLA Mismatches | 3.1 [1.7] | 3.2 [1.7] | 3.3 [1.7] |
| Crossmatch Positive (%) | 1.9 | 5.1 | 5.3 |
| Donor Relationship to Recipient (%) | |||
| Parent | 8.6 | 6.3 | 9.1 |
| Child | 18.5 | 19.2 | 15.3 |
| Sibling | 32.9 | 28.8 | 27.4 |
| Spouse/Life Partner | 12.8 | 13.3 | 21.4 |
| Other Related | 7.1 | 7.8 | 5.4 |
| Other Non-Related | 20.1 | 24.7 | 21.3 |
Age, BMI, %PRA, years of RRT, and HLA mismatches are presented as mean [standard deviation], and all other variables are presented as proportions. ABOc, ABO compatible; ABOi, ABO incompatible; BMI, body mass index; %PRA, percent panel reactive antibody; RRT, renal replacement therapy.