Table 3.
Risk of clinical liver disease progression by YKL-40 promoter polymorphism at rs4950928
| All patients (n=462) | With clinical progression (n=69) | Without clinical progression (n=393) | Hazard ratio (95% CI)* | P-value | |
|---|---|---|---|---|---|
| Homozygous major (CC) | 292 (69.9%) | 44 (66.7%) | 248 (70.5%) | 1 Ref | 0.47 |
| Heterozygous (CT) | 119 (28.5%) | 20 (30.3%) | 99 (28.1%) | 1.19 (0.75, 1.89) | |
| Homozygous minor (TT) | 7 (1.7%) | 2 (3.0%) | 5 (1.4%) | ||
| Missing rs4950928 | 44 | 3 | 41 |
HR calculated assuming an additive model and a continuous variable for genotype status.