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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Antiviral Res. 2012 Jan 10;93(3):322–329. doi: 10.1016/j.antiviral.2011.12.013

FIG.1.

FIG.1

Plots showing the IC50 (nM) ranges of oseltamivir for avian influenza viruses of the N6 subtype isolated from various species of aquatic birds and tested by NAI assay. In panel A isolates are ranked in order by the IC50. Forty-six duck and 27 gull and shorebird isolates were analyzed by the Kruskal-Wallis rank sum test. Panel B shows the number of isolates collected and tested for each group (N = number of isolates) and analyzed by their mean IC50 value (below the N number of isolates). The Kruskal-Wallis test comparing the two groups (ducks and gulls/shorebirds) showed their mean IC50 values (ducks: 1.07 nM; gulls/shorebirds: 3.22 nM) were not significantly different (P ≤ 0.69). Panel C shows quantile box plots illustrating the mean IC50 values for oseltamivir for all avian viruses isolated in different years. The range of isolation years is shown on the X axis. Viruses collected were from various wild birds from the United States and Canada. Results within the graph were analyzed by the Kruskal-Wallis test. No statistical difference was observed among viruses isolated in different years (P<0.74).