Table 2.

Yield and purity (%) of the 96-well plate production of 18 {1–24, 1–4}

R1NH2 (16)	R2NC (17)
	1		2		3		4
	Y	P	Y	P	Y	P	Y	P
1	nr	-	46	100	57	100	53	98
2	nr	-	un	-	un	-	un	-
3	nr	-	45	100	45	100	66	100
4	nr	-	45	100	50	100	65	100
5	69	97	42	100	53	100	64	98
6	49	100	36	100	38	100	55	100
7	50	100	39	100	50	100	54	100
8	57	100	42	100	50	100	62	100
9	57	100	42	100	55	100	49	100
10	56	98	41	100	51	100	60	100
11	23	70	16	100	8	100	13	100
12	47	100	34	100	50	100	53	100
13	46	100	41	100	48	100	63	100
14	49	100	nr	-	38	100	59	100
15	38	100	27	100	43	100	47	100
16	45	100*	47	100	27	100	8	100*
17	56	100	44	100	58	100	61	100
18	51	100	39	100	39	100	61	100
19	26	100	23	100	29	100	33	100
20	55	100	51	100	61	100	83	95
21	59	100	44	100	64	100	72	100
22	7	93*	22	100*	6	100*	2	100*
23	un	-	un	-	un	-	un	-
24	28	96	24	100	18	100	55	100

Y = Yield (%); P = Purity (%) based on UV 214 nm; nr = not recovered/lost during purification; un = no cyclization to 18 observed;

^*purity based on ELS