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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Mamm Genome. 2011 Dec 8;23(3-4):277–285. doi: 10.1007/s00335-011-9380-0

Figure 3.

Figure 3

The B6 allele at Scram1 affects both the overall levels of astrocytoma and the ratio of astrocytomas found in the spinal cord in backcross mice. The incidence of spinal cord astrocytoma compared to all astrocytoma is shown at marker rs4225536, nearest to the Scram1 peak. Statistically significant differences were found between the incidence of total astrocytoma in the two groups (Fisher exact test P = 0.013), the incidence of spinal cord astrocytoma in the two groups (Fisher exact test P <0.0001), and the ratios of spinal cord astrocytoma to total astrocytoma in the two groups (Fisher exact test P = 0.0002). The upward error bar indicates the 95% CI for all astrocytomas and the downward error bar indicates the 95% CI for spinal cord astrocytomas (dark gray). SS indicates the 129/129 genotype at rs4225536 and SB indicates the 129/B6 genotype.