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. Author manuscript; available in PMC: 2013 Apr 1.

Published in final edited form as: Mamm Genome. 2011 Dec 8;23(3-4):277–285. doi: 10.1007/s00335-011-9380-0

Table 1.

Incidence and Latency of Astrocytomas in the Spine and Central Nervous System

		Spinal Cord Astrocytoma			All Astrocyotma (Spine + Brain)

Genotype^**	N	Incidence (% ± CI)	Median Age (mo)	HR [95% CI]	Incidence (% ± CI)	Median Age (mo)	HR [95% CI]
Scram1^129/129, all	41	80 ± 12	8.9	1.9^* [1.1–3.3]	88 ± 10	8.5	1.1 [0.7–1.7]
Scram1^B6/129, all	47	32 ± 13	9.7	1.9^* [1.1–3.3]	64 ± 14	8.8	1.1 [0.7–1.7]
Scram1^129/129, M	22	86 ± 14	9.2	1.5 [0.7–3.1]	91 ± 12	9.0	0.9 [0.5–1.7]
Scram1^B6/129, M	29	34 ± 17	9.8	1.5 [0.7–3.1]	62 ± 18	8.5	0.9 [0.5–1.7]
Scram1^129/129, F	19	74 ± 20	8.5	2.8^* [1.1–6.7]	84 ± 16	8.5	1.4 [0.7–3.2]
Scram1^B6/129, F	18	28 ± 21	9.2	2.8^* [1.1–6.7]	67 ± 22	8.8	1.4 [0.7–3.2]

^*

P <0.05, Kaplan-Meier analysis

^**

Genotype at rs4225536