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Effect of AMN082 on the amphetamine-induced hyperactivity test. AMN082 was given 60 min before amphetamine administration. Locomotor activity was monitored every 10 min over an 80-min session immediately following an injection of psychostimulant agent. The data are presented as means ± SEM and analyzed by repeated measure ANOVA (inset the total activity of mice within the 80-min session was analyzed by one-way ANOVA) # p < 0.001 vs. control group
