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. 2011 Nov 8;40(5):2152–2167. doi: 10.1093/nar/gkr885

Figure 2.

Figure 2.

(A) Effect of Cys, D-amino acids and positioning of Lys residues on Cys-K-PNA23mer-K3 anti-miR activity as seen by luciferase assay. Huh7 cells were treated with 1 µM PNAs. (B) Luciferase assay of Huh7 cells treated with dPNAs at the indicated concentrations in the presence or absence of 10% FBS. (C) Effect of truncations and mismatches on Cys-K-PNA-K3 anti-miR activity as seen by luciferase assay. Huh7 cells were treated with 1 µM PNAs.