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. 2011 Nov 14;40(5):2000–2009. doi: 10.1093/nar/gkr933

Figure 4.

Figure 4.

Genetic interactions between tdp1− and BER mutants. (A) CPT sensitivity in the fission yeast tdp1− strain. Exponentially growing wild-type (FY526) and tdp1− (RHP379) cells were serial diluted in water and spotted onto YES plates containing CPT as indicated. The plates were incubated for 3 days at 30°C and the survival assessed. (B) MMS survival analysis of the tdp1− and BER single and double mutants. Exponentially growing wild-type (FY526), nth1− (RHP357), apn2− (RHP302), tdp1− (RHP379), nth1−apn2− (RHP383), tdp1−nth1− (RHP378), tdp1−apn2− (RHP382) and tdp1−apn2−nth1− (RHP381) cells were serial diluted in water and spotted onto YES plates containing MMS as indicated. The plates were incubated for 3 days at 30°C and the survival assessed.