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. 2011 Nov 15;40(5):2089–2106. doi: 10.1093/nar/gkr983

Figure 5.

Figure 5.

Mph1 DNA helicase activity on 3′-flap-structured DNA. (A) Helicase assays were carried out on 3′-flap-structured substrates as a function of incubation time (0, 1, 2, 5, 15, 30 and 45 min). (B) The results obtained in (A) were plotted against incubation period; note that results from the early time period (0–5 min) are shown. (C) predicted modes of unwinding of 3′-flap-structured DNA by Mph1 are illustrated.