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Role of Bcl-XL or Bim in the development of GVHD. B6 bm12 mice were sublethally irradiated (600 cGy) and transferred with 1 × 106 CD4+ T cells from WT, Bcl-XL Tg or Bim-/- B6 donors. Five recipients were used in each group, and the data show recipient survival (A) and weight loss (B) over time.
