Table 1.

Summary of in vitro and in vivo studies demonstrating efficacy of laser therapy in the treatment of onychomycosis.

Study	In vitro or in vivo	Laser model	Outcome
Vural et al. [19]	In vitro	Q-switched Nd:YAG laser 532-nm and 1064-nm wavelengths	Inhibition of fungal colony growth
Manevitch et al. [20]	In vitro	Femtosecond infrared titanium sapphire	Complete clearance of T. rubrum infected nail clippings after 4 weeks
Kozarev and Mitrovica [21]	In vivo	25-millisecond pulsed Nd:YAG laser 1064 nm wavelength	100% clearance in 42 nails after 3 weeks of treatment
Hochman [22]	In vivo	0.65-millisecond pulsed Nd:YAG laser 1064 nm	7/8 cleared after 9 weeks of treatment
Landsman et al. [23]	In vivo	Dual-wavelength near-infrared diode laser with 830-nm and 970-nm wavelengths	22/26 demonstrated improvement after 4 months of treatment