Table 2. Daily and 3-day average comparison of subjective appetite measurements calculated as mean area under the curve in response to placebo or PGX for the per-protocol subject group.

Score	Day	Placebo	PGX	% Change	P-value
Prospective consumption	1	457.2±29.4	432.5±27.8	−5.4	0.358
	2	477.9±33.1	427.1±29.6	−10.6	0.079
	3	471±32.5	401.8±27.7	−14.7	0.017
	Average days 1–3	468.6±28.9	420.2±25.9	−10.3	0.026
Desire	1	432.5±29.4	428.8±29.1	−0.9	0.894
	2	456.3 ±34.2	416.9±31.3	−8.6	0.273
	3	427.7±35	387.9±31.7	−9.3	0.280
	Average days 1–3	438.6±29.7	410.8±27.8	−6.3	0.303
Fullness	1	598.3±40.3	591.6±39.9	−1.1	0.832
	2	584.5±50.7	574.5±49.8	−1.7	0.785
	3	614.1±47.2	632.3±48.6	3	0.592
	Average days 1–3	598.8±43.8	599±43.9	0	0.996
Hunger	1	431.5±28.6	418.3±27.7	−3.1	0.651
	2	434.9±33.6	407.6±31.5	−6.3	0.429
	3	440.4±32.9	375.4±28	−14.8	0.048
	Average days 1–3	435.6±28.4	400±26.1	−8.2	0.162
Total appetite	1	469.8±27.3	458.7±26.7	−2.4	0.675
	2	475.9±31.8	449.4±30.0	−5.6	0.390
	3	464.5±31.9	414.3±28.4	−10.8	0.106
	Average days 1–3	470±27.9	440.4±26.2	−6.3	0.215

Abbreviation: PGX, PolyGlycopleX.

Note: P-value is from a linear mixed-model fit on log scale of area under curve and adjusting for potential sequence and period effects in addition to treatment (significance level P<0.05).

Values shown are mean±s.e.; n=35.