Table 5. Intermediate metabolite concentrations of fecal samples from obese and normal-weight children assessed by HPLC.
Metabolite |
Obese |
Normal-weight |
P-value | ||
---|---|---|---|---|---|
ma | s.d. | ma | s.d. | ||
Lactose | 0.01 | ±0.04 | 0.07 | ±0.17 | 0.15 |
Glucose | 4.28 | ±5.23 | 26.61 | ±61.73 | 0.11 |
Lactate | 0.80 | ±0.77 | 12.02 | ±14.3 | 0.009* |
Formate | 1.22 | ±4.73 | 0.24 | ±1.12 | 0.44 |
Isobutyrate | 7.87 | ±2.7 | 3.11 | ±2.11 | 0.0007* |
Isovalerate | 2.33 | ±2.45 | 3.05 | ±2.33 | 0.38 |
Valerate | 0.97 | ±1.27 | 2.09 | ±1.56 | 0.02* |
Abbreviations: HPLC, high-pressure liquid chromatography; s.d., standard deviation of the means.
Data are mean values calculated for fecal samples of each group (obese: n=15; normal-weight: n=15).
Intermediate metabolite concentrations that are significantly different are denoted by *P<0.05.