Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Mar 12;209(3):437–444. doi: 10.1084/jem.20111923

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2012 Cook et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 2. — Intratumoral measurements of MRK003 and gemcitabine and tumor volumes. (A) Concentration of MRK003 in PDA tissue after monotherapy (n = 6) and GSI/gemcitabine combination treatment (n = 6; P = 0.18). (B) Ratio of MRK003 in other organs compared with the amount in a tumor in two different mice. (C) Concentration of gemcitabine and its metabolites in whole tumor samples (n = 6 on all cohorts). All animals were treated for 10 d then sacrificed 1 h after the last dose of gemcitabine and 6 h after the last dose of MRK003. Error bars represent SEM.