Fig 4.

(A) Recognition of irradiated viruses by MAb 14G7 and recognition of recombinant viral glycoproteins by MAbs 14G7, 13F6-1-2, 42/3.7, and KZ52. +, Positive binding. –, no binding. Blank lines = not done. Only 14G7 was tested against irradiated virus samples. (B) Neutralization of VP30-deleted, biologically contained Ebola viruses (ΔVP30 EBOV). ΔVP30 EBOV was incubated with either MAb 14G7, 13F6-1-2, 42/3.7, or KZ52 in the presence or absence of guinea pig complement and allowed to attach to Vero E6 cells at 4°C. The cells were washed of unbound material, warmed to 37°C, and plaqued.