Table 4.
Biodistribution test regimens
| Animals | Regimen | Testing schedule for biodistribution assaysa |
|---|---|---|
| A08404, A08132, A08760, A09134, A09763, 30027 | Complete | Adrenals, aorta, cecum, cerebrum, cerebellum, colon, CSF, duodenum, epididimy (in males), esophagus, eye, femur, gallbladder, gonads, heart, ileum, jejunum, kidney, liver, lung, mammary gland, mandibular LN, mediastinal LN, mesenteric LN, motor cortex, muscle, optic nerve, pancreas, pons/medulla, rib, salivary gland, sciatic nerve, skin, spinal cord, spleen, stomach, sternum, thymus, thyroid/parathyroid, tonsils, trachea, urinary bladder |
| A06682, A08813, A09163 | Select | Cerebrum, cerebellum, colon, CSF, mandibular LN, mediastinal LN, mesenteric LN, motor cortex, pons/medulla, spinal cord |
| A09158, A09750, A10107, A10129 | CNS | Cerebrum, cerebellum, CSF, motor cortex, pons/medulla, spinal cord |
a
CSF, cerebrospinal fluid; LN, lymph nodes.