Fig 2.

The serum antibody response to peptide I and peptide II is maintained over time. Sequential serum samples obtained from patients 1A76 and 3A64 were tested for reactivity to immobilized peptide I (corresponding to the region of E2 encompassing aa 412 to 423) and peptide II (E2 region encompassing aa 434 to 446) in an enzyme immunoassay. (A) 1A76-Ig reactivity to peptide I (■) or peptide II (□). (B) 3A64-Ig reactivity to peptide I (●) or peptide II (○). Arrows indicate the samples used as a source of immunoglobulin fractions for subsequent analyses. OD₄₀₅, optical density at 405 nm.