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. 2012 Mar;86(6):3073–3087. doi: 10.1128/JVI.05640-11

Fig 1.

Fig 1

Viruses used in this study. VSV-p1-GFP has the GFP ORF inserted in position 1 of the viral genome, resulting in attenuation of the virus. VSV-ΔM51-GFP has a deletion at amino acid position 51 of the M protein, reducing its ability to suppress host immunity. In addition, VSV-ΔM51-GFP has the GFP ORF inserted in position 5 of the viral genome. SeV-GFP has the GFP ORF inserted at position 1 of the viral genome and a mutation in the cleavage site of the F protein, allowing F activation and production of infectious virus particles in cells without trypsin addition. RSV-GFP has the GFP ORF inserted at position 1 of the viral genome. CRAd-dl1520 is attenuated by deletion of a large part of the coding sequence for the E1b55k viral gene product. CRAd-hTERT is an hTERT-dependent CRAd.