Table 1.

Viruses employed

Virus species	Abbreviation	Genotype	Family	Genus	Genome structurea	No. of genome segments	No. of sequences	Genome size (bp)	Coding capacity (aa)b	Avg pairwise identity (%)
Hepatitis C virus	HCV	1a	Flaviviridae	Hepacivirus	ssRNA, + polarity	1	300	9,033	3,011	94.9
		1b					300	9,030	3,010	94.2
GB virus C	GBV-C		Flaviviridae	Unassigned	ssRNA, + polarity	1	27	9,392	2,842	96.6
Dengue virus	DV	2	Flaviviridae	Flavivirus	ssRNA, + polarity	1	100	10,173	3,391	98.2
West Nile virus	WNV		Flaviviridae	Flavivirus	ssRNA, + polarity	1	64	11,000	3,448	98.9
Hepatitis A virus	HAV		Picornaviridae	Hepativirus	ssRNA, + polarity	1	33	7,478	2,228	98.2
Poliovirus	PV	1	Picornaviridae	Enterovirus	ssRNA, + polarity	1	63	7,441	2,209	97.7
Hepatitis E virus	HEV	3	Hepeviridae	Hepevirus	ssRNA, + polarity	1	41	7,176	2,432c	97.8
Crimean-Congo hemorrhagic fever virus	CCHV		Bunyaviridae	Nairovirus	ssRNA, + polarity	3	24	19,146	5,871d	94.8
Rabies virus	RV	1	Rhabdoviridae	Lyssavirus	ssRNA, − polarity	1	26	11,932	3,600	95.8
Hepatitis delta virus	HDV	1	Unassigned	Deltavirus	ssRNA, − polarity	1	75	1,680	195e	85.1
Influenza virus	IV-A	A	Orthomyxoviridae	Influenzavirus A	ssRNA, − polarity	8	32	13,400	4,555	99.1
Parvovirus B19	B19	2	Parvoviridae	Erythrovirus	ssDNA, mixed polarity	1	20	5,594	1,452	98.0
Hepatitis B virus	HBV	B	Hepadnaviridae	Orthohepadnavirus	Partially double-stranded DNA	1	100	3,221	1,609	97.3
		C					100	3,215	1,609	95.9
		D					100	3,182	1,587	97.1

^ass, single stranded; +, positive; −, negative.

^baa, amino acids.

^cCoding sequences for CDS1 were edited to remove the repetitive region.

^dCoding sequences for the M segment were edited to remove the highly variable first 240 aa.

^eSmall form of the HDV delta antigen.