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Viral DNA synthesis in AdEasyE1-infected and AdEasyE1Δ2347 mutant-infected NHBECs. Proliferating NHBECs at ∼60% confluence (A) or quiescent NHBECs (B) were infected with 5 PFU/cell AdEasy E1 or the AdEasyE1Δ2347 mutant, and viral DNA concentrations were measured at the times indicated (see Materials and Methods). The values shown represent the mean of two independent experiments, and the error bars indicate average deviations. In all panels: WT, AdEasyE1; Δ2347, the AdEasyE1Δ2347 mutant.
