Table 3.

Comparison of Predisposing Factors for Delirium after Hip Fracture Repair by Pre-Operative Dementia Status

	No Dementia (N = 284)		Probable Dementia (N =141)
Variables	Crude OR (95% CI)	p-value	Crude OR (95% CI)	p-value
age –in years	1.07 (1.05, 1.08)	0.020	1.00 (0.93, 1.07)	0.843
gender - male	2.06 (1.16, 3.63)	0.012	1.85 (0.85, 4.02)	0.119
race - white	0.89 (0.23, 3.44)	0.708	0.54 (0.39, 5.93)	0.413
current smoking	0.55 (0.25, 1.25)	0.198	1.39 (0.54, 3.61)	0.486
current alcohol use	0.59 (0.23, 1.48)	0.399	1.86 (0.61, 5, 69)	0.293
body-mass index-bmi (kg/m2)	0.93 (0.88, 0.99)	0.025	1.06 (0.98, 1.14)	0.151
underweight: bmi <18.50	1.23 (0.52, 2.90)	0.638	0.86 (0.29, 2.56)	0.781
normal: 18.50≤ bmi < 25.00	REF	N/A	REF	N/A
overweight: bmi ≥ 25.00	0.63 (0.34, 1.19)	0.152	1.48 (0.61, 3.58)	0.382
pre-operative MMSE	0.77 (0.60, 0.99)	0.039	0.93 (0.83, 1.05)	0.274
Katz ADL index	0.74 (0.52, 1.06)	0.098	0.90 (0.69, 1.17)	0.422
Lawton IADL scale	0.89 (0.76, 1.03)	0.123	0.99 (0.84, 1.17)	0.916
Medical History
# of medical comorbidities	1.14 (1.03, 1.27)	0.023	1.09( 0.95, 1.25)	0.201
CVA or TIA	1.15 (0.77, 3.03)	0.225	1.22 (0.57, 2.59)	0.613
# of prescription meds	1.32 (1.02, 1.70)	0.034	0.95 (0.74, 1.20)	0.651
ASA rating 4 or above	2.45 (1.12, 5.25)	0.022	1.30 (0.54, 3.14)	0.555
history of depression	1.13 (0.53, 2.39)	0.758	0.98 (0.43, 2.26)	0.919
Pre-operative variables
Type of fracture
femoral neck	REF	N/A	REF	N/A
Intertrochanteric	0.87 (0.51.1.49)	0.621	0.99 (0.51.1.94)	0.994
Pre-op serological abnormality
hematocrit <30	1.52 (0.65, 3.56)	0.328	0.72 (0.23, 2.26)	0.573
bun/creatinine >20	0.71 (0.41, 1.22)	0.211	0.97 (0.47, 1.99)	0.932
WBC>12,000	0.74 (0.39, 1.40)	0.200	1.03 (0.51, 2.08)	0.936
sodium <130	2.25 (0.87, 5.83)	0.088	1.16 (0.25, 5.41)	0.846
albumin <3.5 or >4.5	1.30 (0.71, 3.72)	0.246	1.48 (0.60, 3.65)	0.396
ER to surgery – in hours	1.00 (0.99, 1.02)	0.417	1.01 (1.00, 1.03)	0.042
ER to surgery > 36 hours	0.81 (0.42, 1.58)	0.536	2.83 (1.24, 6.48)	0.017
Intraoperative Variables
Type of surgery
Hemiarthroplasty	REF	N/A	REF	N/A
Screw and side plate	0.84 (0.35, 2.05)	0.710	0.84 (0.35, 2.06)	0.710
Intramedullary hip screw	0.39 (0.18, 0.94)	0.034	0.72 (0.28, 1.90)	0.509
Cannulated screw	0.56 (0.14, 1.09)	0.072	1.72 (0.54, 5,56)	0.359
Others	0.70 (0.21, 2.28)	0.548	0.47 (0.10, 2.16)	0.334
Type of anesthesia –general	1.40 (0.79, 2.48)	0.254	1.15 (0.58, 2.25)	0.692
Length of surgery – hours, (sd)	1.36 (1.03, 1.79)	0.030	0.98 (0.69, 1.42)	0.919
Length of surgery >2 hours	1.99 (1.14, 3.47)	0.017	1.02 (0.52, 1.98)	0.960
Transfusion >2 units of RBC	2.60 (1.33, 5.08)	0.004	0.98 (0.40, 2.41)	0.965