TABLE 3.

Serum lipid profile at baseline and after 4 wk of treatment¹

	Placebo			Plant sterols			P value2
Lipid variables and group	Day 1	Day 29	Change	Day 1	Day 29	Change	Treatment	Group	Interaction
Total cholesterol (mmol/L)
HET	5.03 ± 0.27	5.09 ± 0.23	0.06 ± 0.23	5.23 ± 0.17	4.76 ± 0.19	−0.46 ± 0.13	0.003	0.187	0.746
Control	5.63 ± 0.23	5.84 ± 0.26	0.21 ± 0.13	5.85 ± 0.22	5.63 ± 0.24	−0.22 ± 0.10
LDL cholesterol (mmol/L)
HET	3.13 ± 0.23	3.12 ± 0.20	−0.01 ± 0.16	3.09 ± 0.16	2.73 ± 0.19	−0.36 ± 0.18	0.006	0.073	0.403
Control	3.20 ± 0.17	3.50 ± 0.21	0.31 ± 0.10	3.43 ± 0.19	3.11 ± 0.19	−0.32 ± 0.10
HDL cholesterol (mmol/L)
HET	1.37 ± 0.13	1.27 ± 0.10	−0.10 ± 0.06	1.48 ± 0.14	1.36 ± 0.11	−0.12 ± 0.07	0.232	0.057	0.438
Control	1.14 ± 0.06	1.21 ± 0.06	0.07 ± 0.05	1.25 ± 0.08	1.19 ± 0.06	−0.06 ± 0.06
Triglycerides (mmol/L)
HET	1.31 ± 0.11	1.55 ± 0.29	0.24 ± 0.19	1.62 ± 0.23	1.52 ± 0.25	−0.10 ± 0.14	0.210	0.597	0.001
Control	2.91 ± 0.45	2.51 ± 0.37	−0.40 ± 0.16	2.63 ± 0.44	2.97 ± 0.48	0.34 ± 0.15

¹All values are means ± SEMs; n = 10 (HET) and 15 (Control). Day 1 represents baseline, and Day 29 represents the endpoint of each 4-wk treatment period. HET, phytosterolemia heterozygote.

²Differences between groups and treatments were assessed by repeated-measures 2-factor ANOVA; P < 0.05 is considered significant.