Table 1.
Clinical and virological parameters of HCV infected patients included in the study
| Liver biopsy specimena | Sexb | Fibrosis stage | Grade of activity | HCV viral load (IU/ml) | Rheumatoid factor (amt [IU/ml]c | Serum albumin (g/dl)d | Alkaline phosphatase (U/liter)e | Total C3 level (mean ± SD [mg/dl]) |
|---|---|---|---|---|---|---|---|---|
| 158 | M | 1 | 6,687,000 | − | 4.6 | 85 | 46.8 ± 2.2 | |
| 164 | M | 2 | Mild activity, grade 2 | 1,095,730 | − | 4.8 | 82 | 46.6 ± 2.7 |
| 165 | F | 3 | Mild activity, grade 2 | 1,001,400 | − | 48.3 ± 1.4 | ||
| 167 | F | 0 | 928,400 | − | 4.3 | 82 | 52.2 ± 0.85 | |
| 170 | M | 0 | 69,000,000 | − | 50.7 ± 1.3 | |||
| 171 | F | 3 | Mild activity grade 2 | 2,69,0000 | − | 4.5 | 110 | 43.6 ± 1.6 |
| 173 | F | 2 | Periportal fibrosis, mild activity, grade 2 | 432,700 | + (240) | 4.5 | 84 | 49.8 ± 1.3 |
| 176 | M | 1 | Stage 1 activity | 1,87,2412 | − | 4.6 | 67 | 52.8 ± 1.4 |
| 180 | M | 1 | Stage 2 activity | 3,624,000 | − | 4.1 | 78 | 47.8 ± 2.8 |
| 181 | F | 3 | Stage 2 activity | 3,929,434 | − | 3.8 | 82 | 48.4 ± 1.7 |
| 183 | F | 1 | Mild activity, grade 2 | 160,700 | + (480) | 4.1 | 89 | 55.8 ± 1.6 |
| 186 | M | 2 | Stage 2 activity | 5,690,000 | − | 4.5 | 50 | 43.7 ± 2.9 |
a
All 12 patients were infected with HCV genotype 1a.
b
M, male; F, female.
c
The presence (+) or absence (−) of rheumatoid factor in blood is indicated.
d
The normal range is 3.4 to 5.5 g/dl.
e
The normal range is 33 to 133 U/liter.