Figure 7.

Expression of BCRP in mouse retina and in primary cultures of mouse RPE cells, Müller cells, and ganglion cells. (A) BCRP mRNA was analyzed by RT-PCR using RNA samples prepared from neural retina and RPE-eyecup from 3-month-old C57BL/6 mice. (B) BCRP mRNA was analyzed by RT-PCR using RNA samples prepared from primary mouse RPE cells (1° RPE), Müller cells (1° MC), and ganglion cells (1° GC). (C) Analysis of BCRP protein by immunofluorescence in mouse (BALB/c) retina. GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer.