Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A model for the inhibitory effects MdmX exerts on p53. MdmX inhibits p53 both directly, through binding to its trans-activation domain and preventing it from recruiting transcriptional coactivators and indirectly, through promoting the activation of the p53 inhibitors Mdm2 and Wip1.
