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. 2012 Apr;86(7):3952–3960. doi: 10.1128/JVI.06627-11

Fig 2.

Fig 2

Genomewide pyrosequencing of HCV-2b/1a DNA clone in order to determine error rates associated with PCR and Roche/454 pyrosequencing. (A) Sequence coverage obtained across the HCV-2b/1a genome. The HCV-2b/1a genomic organization is depicted at the top of the figure. The nucleotide numbering is based on the sequence of HCV strain H77 (GenBank accession no. NC_004102). (B) Graph indicating the SNP frequency across the HCV-2b/1a genome on a 50% y axis (top) and 1% y axis (bottom). The HCV-2b/1a genomic organization is depicted at the top of the figure. The nucleotide numbering is based on the sequence of HCV strain H77 (GenBank accession no. NC_004102).