Table 2.

FK506 and FK520 titers from Streptomyces sp. KCTC 11604BP and mutant strains

Macrolide	Antibiotic titer (mg liter−1)a ± SD for strain:
	Wild type	WT/pTCS2	WT/pTCS7	WT/pFKBN	Δtcs2	Δtcs7	ΔfkbN	ΔfkbN/pTCS2	ΔfkbN/pTCS7	ΔfkbN/pFKBN
FK506	5.22 ± 0.65	5.18 ± 0.27	4.51 ± 0.98	11.1 ± 0.48	5.12 ± 0.51	9.89 ± 0.98	NDb	ND	ND	5.24 ± 0.71
FK520	0.65 ± 0.06	0.61 ± 0.03	0.59 ± 0.08	1.39 ± 0.04	0.61 ± 0.08	0.97 ± 0.82	ND	ND	ND	0.79 ± 0.09

^aStandard error values are the results of two series of duplicate data acquisition.

^bND, not detected.