Table 1.
Patient and donor characteristics by treatment group: Tac/SRL versus Tac/MMF
| Characteristics | Tac/SRL (n=37) | Tac/MMF (n=45) | P Valuea | ||
|---|---|---|---|---|---|
| n | Percent | n | Percent | ||
| Age in years (mean±SD) | 45.7±13.4 | 42.3±11.9 | 0.24 | ||
| Race | 0.87 | ||||
| white | 25 | 67.6 | 30 | 66.7 | |
| African American | 10 | 27.0 | 11 | 24.4 | |
| Hispanic | 1 | 2.7 | 1 | 2.2 | |
| Asian | 1 | 2.7 | 3 | 6.7 | |
| Sex | 0.80 | ||||
| male | 22 | 59.5 | 28 | 62.2 | |
| female | 15 | 40.5 | 17 | 37.8 | |
| Diabetes | 0.21 | ||||
| yes | 7 | 18.9 | 4 | 8.9 | |
| no | 30 | 81.1 | 41 | 91.1 | |
| Degree of mismatch in number of Ags (mean±SD) | 3.1±2.0 | 3.6±1.8 | 0.25 | ||
| PRA (percent) >25% | 3 | 8 | 0 | 0 | 0.99 |
| Donor type | 0.77 | ||||
| deceased | 10 | 27.0 | 15 | 33.3 | |
| living | 20 | 54.1 | 21 | 46.7 | |
| living (unrelated) | 7 | 18.9 | 9 | 20.0 | |
| Donor age in years (mean±SD) | 39.7±13.3 | 33.3±11.5 | 0.03 | ||
| DGF | 4 | 10.8 | 0 | 0.0 | 0.02 |
Tac, tacrolimus; SRL, sirolimus; MMF, mycophenolate mofetil; Ags, antigens; PRA, Panel reactive antibody; DGF, delayed graft function.
a
t test for continuous variables; chi-squared or Fisher exact test for categorical variables.